40647-02-7
Chemical Structure
BTO-1
- CAS No.: 40647-02-7
- Formula:C9H4N4O4S
- Molecular Weight:264.22
IUPAC Name: 2-carbamoyl-5-cyano-7-nitrobenzo[d]thiazole 3-oxide
InChIKey: FKRBAXZAJBBIAJ-UHFFFAOYSA-N
SMILES: O=C(C1=[N+]([O-])C2=CC(C#N)=CC([N+]([O-])=O)=C2S1)N
Biological Activity: BTO-1 is a Polo-like kinase (Plk) inhibitor. BTO-1 is primarily used for phosphorylation and dephosphorylation applications[1][2].
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BTO-1 | BTO-1 is a Polo-like kinase (Plk) inhibitor. BTO-1 is primarily used for phosphorylation and dephosphorylation applications. | |||||||||||||||||||||
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- [1]. Peters, U., et al. Probing cell-division phenotype space and Polo-like kinase function using small molecules. Nat Chem Biol 2, 618–626 (2006).
- [2]. Brennan IM, et al. Polo-like kinase controls vertebrate spindle elongation and cytokinesis. PLoS One. 2007;2(5):e409. Published 2007 May 2. [Content Brief]
Keywords