421580-53-2
Chemical Structure
Corr4A
- CAS No.: 421580-53-2
- Formula:C21H17ClN4O2S2
- Molecular Weight:456.97
IUPAC Name: N-(2-((5-chloro-2-methoxyphenyl)amino)-4'-methyl-[4,5'-bithiazol]-2'-yl)benzamide
InChIKey: RDOBOPJBMQURAT-UHFFFAOYSA-N
SMILES: O=C(NC1=NC(C)=C(C2=CSC(NC3=CC(Cl)=CC=C3OC)=N2)S1)C4=CC=CC=C4
Biological Activity: Corr4A is a chemical corrector, which can be used for cystic fibrosis. Corr4A interacts directly with the cystic fibrosis transmembrane conductance regulator (CFTR) or affects indirectly its folding process. Corr4A increases the expression of CFTR ΔF508 on the cell surface, thereby improving its transport to the plasma membrane and increasing the stability of the rescued mutant protein[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Corr4A | 99.58% | Corr4A is a chemical corrector, which can be used for cystic fibrosis. Corr4A interacts directly with the cystic fibrosis transmembrane conductance regulator (CFTR) or affects indirectly its folding process. Corr4A increases the expression of CFTR ΔF508 on the cell surface, thereby improving its transport to the plasma membrane and increasing the stability of the rescued mutant protein. | ||||||||||||||||||||
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Keywords
