425632-67-3
425632-67-3
Chemical Structure
VPLSLYSG
- CAS No.: 425632-67-3
- Formula:C39H62N8O12
- Molecular Weight:834.96
InChIKey: OSAJHMOJCFGRBU-LGICIMODSA-N
SMILES: OC(C=C1)=CC=C1C[C@@H](C(N[C@@H](CO)C(NCC(O)=O)=O)=O)NC([C@H](CC(C)C)NC([C@H](CO)NC([C@H](CC(C)C)NC([C@H]2N(CCC2)C([C@@H](N)C(C)C)=O)=O)=O)=O)=O
Biological Activity: VPLSLYSG is an octapeptide that can be degraded by matrix metalloproteinase-9 (MMP-9), MMP-1 and MMP-2. VPLSLYSG has potential applications in MMP substrates[1][2][3].
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VPLSLYSG | VPLSLYSG is an octapeptide that can be degraded by matrix metalloproteinase-9 (MMP-9), MMP-1 and MMP-2. VPLSLYSG has potential applications in MMP substrates. | |||||||||||||||||||||
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References
- [1]. Suzuki H, et al. Accurate targeting of activated macrophages based on synergistic activation of functional molecules uptake by scavenger receptor and matrix metalloproteinase. ACS Chem Biol. 2008 Aug 15;3(8):471-9. [Content Brief]
- [2]. Patterson J, et al. Enhanced proteolytic degradation of molecularly engineered PEG hydrogels in response to MMP-1 and MMP-2. Biomaterials. 2010 Oct;31(30):7836-45. [Content Brief]
- [3]. Wieduwild R, et al. Assembling and decorating hyaluronan hydrogels with twin protein superglues to mimic cell-cell interactions. Biomaterials. 2018 Oct;180:253-264. [Content Brief]
