430458-66-5
430458-66-5
Chemical Structure
MMRi64
- CAS No.: 430458-66-5
- Formula:C22H17Cl2N3O
- Molecular Weight:410.30
IUPAC Name: 7-((2,3-dichlorophenyl)((4-methylpyridin-2-yl)amino)methyl)quinolin-8-ol
InChIKey: HQICAVDTVBACIN-UHFFFAOYSA-N
SMILES: OC1=C2N=CC=CC2=CC=C1C(C3=CC=CC(Cl)=C3Cl)NC4=NC=CC(C)=C4
Biological Activity: MMRi64 disrupts Mdm2-MdmX interactions. MMRi64 downregulates Mdm2 and MdmX in leukemia cells. MMRi64 induces p53 accumulation, and induces the apoptotic arm of the p53 pathway in leukemia/lymphoma cells. MMRi64 can be used for cancer research[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
MMRi64 | 99.42% | MMRi64 disrupts Mdm2-MdmX interactions. MMRi64 downregulates Mdm2 and MdmX in leukemia cells. MMRi64 induces p53 accumulation, and induces the apoptotic arm of the p53 pathway in leukemia/lymphoma cells. MMRi64 can be used for cancer research. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
Keywords
