430458-66-5
430458-66-5
Chemical Structure
MMRi64
- CAS No.: 430458-66-5
- Formula:C22H17Cl2N3O
- Molecular Weight:410.30
IUPAC Name: 7-((2,3-dichlorophenyl)((4-methylpyridin-2-yl)amino)methyl)quinolin-8-ol
InChIKey: HQICAVDTVBACIN-UHFFFAOYSA-N
SMILES: OC1=C2N=CC=CC2=CC=C1C(C3=CC=CC(Cl)=C3Cl)NC4=NC=CC(C)=C4
Biological Activity: MMRi64 disrupts Mdm2-MdmX interactions. MMRi64 downregulates Mdm2 and MdmX in leukemia cells. MMRi64 induces p53 accumulation, and induces the apoptotic arm of the p53 pathway in leukemia/lymphoma cells. MMRi64 can be used for cancer research[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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MMRi64 | 99.42% | MMRi64 disrupts Mdm2-MdmX interactions. MMRi64 downregulates Mdm2 and MdmX in leukemia cells. MMRi64 induces p53 accumulation, and induces the apoptotic arm of the p53 pathway in leukemia/lymphoma cells. MMRi64 can be used for cancer research. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.87
HY-148409MMRi62 -
Similarity Score 0.77
HY-175837EGFR-IN-172 -
Similarity Score 0.70
HY-18670HQ-415 -
Similarity Score 0.67
HY-101449RAdaptaquin (Standard) -
Similarity Score 0.66
HY-124791MMRi6 -
Similarity Score 0.66
HY-18671BoNT-IN-1 -
Similarity Score 0.64
HY-12826IMB-XH1 -
Similarity Score 0.62
HY-139464Q134R -
Similarity Score 0.60
HY-16667HLM006474 -
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