4310-35-4
Chemical Structure
Tridihexethyl chloride
Synonym(s): Pathilon chloride
- CAS No.: 4310-35-4
- Formula:C21H36ClNO
- Molecular Weight:353.97
IUPAC Name: 3-cyclohexyl-N,N,N-triethyl-3-hydroxy-3-phenylpropan-1-aminium chloride
InChIKey: XJGONMZLEDGBRM-UHFFFAOYSA-M
SMILES: OC(CC[N+](CC)(CC)CC)(C1CCCCC1)C2=CC=CC=C2.[Cl-]
Biological Activity: Tridihexethyl (Pathilon) chloride is an orally active anticholinergic agent and mAChR antagonist, shows activities of antimuscarinic and anticholinergic. Tridihexethyl chloride shows pronounced antispasmodic and antisecretory effects on the gastrointestinal tract. Tridihexethyl chloride can be used in studies of peptic ulcer disease and acquired nystagmus [1][2].
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Tridihexethyl chloride | 96.45% | Tridihexethyl (Pathilon) chloride is an orally active anticholinergic agent and mAChR antagonist, shows activities of antimuscarinic and anticholinergic. Tridihexethyl chloride shows pronounced antispasmodic and antisecretory effects on the gastrointestinal tract. Tridihexethyl chloride can be used in studies of peptic ulcer disease and acquired nystagmus . | ||||||||||||||||||||
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Similarity Score 0.76
HY-B1487RProcyclidine hydrochloride (Standard) -
Similarity Score 0.76
HY-B1277RTrihexyphenidyl hydrochloride (Standard) -
Similarity Score 0.76
HY-B1487AProcyclidine -
Similarity Score 0.75
HY-119918Cycrimine -
Similarity Score 0.75
HY-B1277ATrihexyphenidyl -
Similarity Score 0.67
HY-W103877R2-Cyclohexyl-2-hydroxy-2-phenylacetic acid (Standard) -
Similarity Score 0.66
HY-W157189Methyl 2-cyclohexyl-2-hydroxyphenylacetate -
Similarity Score 0.66
HY-129709DAC 5945 -
Similarity Score 0.65
HY-W013534RGlycopyrronium impurity 4 (Standard) -
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References
- [1]. Leigh RJ, et al. Effect of anticholinergic agents upon acquired nystagmus: a double-blind study of trihexyphenidyl and tridihexethyl chloride. Neurology. 1991 Nov;41(11):1737-41. [Content Brief]
- [2]. Jabbari B, et al. ffectiveness of trihexyphenidyl against pendular nystagmus and palatal myoclonus: evidence of cholinergic dysfunction. Mov Disord. 1987;2(2):93-8. [Content Brief]