4329-78-6
Chemical Structure
Xanthine oxidoreductase-IN-6
- CAS No.: 4329-78-6
- Formula:C12H9N5
- Molecular Weight:223.24
IUPAC Name: 4,4'-(1H-1,2,4-triazole-3,5-diyl)dipyridine
InChIKey: QUKGHTHKDNHSOX-UHFFFAOYSA-N
SMILES: C1(C2=CC=NC=C2)=NNC(C3=CC=NC=C3)=N1
Biological Activity: Xanthine oxidoreductase-IN-6 (Compound 4) is an orally active xanthine oxidoreductase (XOR) inhibitor with an IC50 of 170 nM. Xanthine oxidoreductase-IN-6 can block the final step of uric acid biosynthesis and lower serum uric acid levels. Xanthine oxidoreductase-IN-6 also shows Cytochrome P450 3A4 (CYP3A4) inhibitory activity. Xanthine oxidoreductase-IN-6 can be used for the research of hyperuricemia[1].
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Xanthine oxidoreductase-IN-6 | 99.83% | Xanthine oxidoreductase-IN-6 (Compound 4) is an orally active xanthine oxidoreductase (XOR) inhibitor with an IC50 of 170 nM. Xanthine oxidoreductase-IN-6 can block the final step of uric acid biosynthesis and lower serum uric acid levels. Xanthine oxidoreductase-IN-6 also shows Cytochrome P450 3A4 (CYP3A4) inhibitory activity. Xanthine oxidoreductase-IN-6 can be used for the research of hyperuricemia. | ||||||||||||||||||||
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Keywords