454453-49-7
454453-49-7
Chemical Structure
Kobe2602
- CAS No.: 454453-49-7
- Formula:C14H9F4N5O4S
- Molecular Weight:419.31
IUPAC Name: 2-(2,6-dinitro-4-(trifluoromethyl)phenyl)-N-(4-fluorophenyl)hydrazine-1-carbothioamide
InChIKey: NNPBSITXCGPXJC-UHFFFAOYSA-N
SMILES: FC(C1=CC([N+]([O-])=O)=C(NNC(NC2=CC=C(F)C=C2)=S)C([N+]([O-])=O)=C1)(F)F
Biological Activity: Kobe2602 is a Ras-Raf interaction inhibitor. Kobe2602 inhibits the binding of H-Ras·GTP to c-Raf-1 RBD with a Ki of 149 μM. Kobe2602 has antitumor activity[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Kobe2602 | 98.20% | Kobe2602 is a Ras-Raf interaction inhibitor. Kobe2602 inhibits the binding of H-Ras·GTP to c-Raf-1 RBD with a Ki of 149 μM. Kobe2602 has antitumor activity. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.81
HY-15716Kobe0065 -
Similarity Score 0.70
HY-119230Kobe2601 -
Similarity Score 0.61
HY-122228Cestrin -
Similarity Score 0.54
HY-W874850RFluorodifen (Standard) -
Similarity Score 0.53
HY-138280DTHIB -
Similarity Score 0.52
HY-135466RProfluralin (Standard) -
Similarity Score 0.52
HY-W714214Ethalfluralin -
Similarity Score 0.51
HY-B2050Trifluralin -
Similarity Score 0.51
HY-B2045RBenfluralin (Standard) -
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