4546-39-8
4546-39-8
Chemical Structure
Piperilate
Synonym(s): Pipethanate
- CAS No.: 4546-39-8
- Formula:C21H25NO3
- Molecular Weight:339.43
IUPAC Name: 2-(piperidin-1-yl)ethyl 2-hydroxy-2,2-diphenylacetate
InChIKey: RZWPJFMNFATBEG-UHFFFAOYSA-N
SMILES: O=C(OCCN1CCCCC1)C(C2=CC=CC=C2)(C3=CC=CC=C3)O
Biological Activity: Piperilate (Pipethanate) is one of the mixtures of hetrazepine derivative PAF antagonists with anticholinergics, can be used for bronchial asthma research. Piperilate also causes hypotension and rescues mice poisoned by the organophosphates[1][2][3].
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Piperilate | Piperilate (Pipethanate) is one of the mixtures of hetrazepine derivative PAF antagonists with anticholinergics, can be used for bronchial asthma research. Piperilate also causes hypotension and rescues mice poisoned by the organophosphates. | |||||||||||||||||||||
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References
- [1]. Faff J, et al. Therapeutic effects of some cholinolytics in organophosphate intoxications. Arch Toxicol. 1976 Oct 28;36(2):139-46. [Content Brief]
- [2]. Tanaka S, et al. [Studies on pharmacological effect of pipethanate. II. Effect of pipethanate on respiration, circulation system and smooth muscle]. Eisei Shikenjo Hokoku. 1971;89:54-8. Japanese. [Content Brief]
- [3]. Heuer, et al. Synergistic combinations of PAF antagonists and anticholinergic agents as drugs for treatment of bronchial asthma: Germany, DE4219659. 1993-12-23.
Keywords
