475498-26-1
Chemical Structure
MCL0020
- CAS No.: 475498-26-1
- Formula:C34H39N7O4
- Molecular Weight:609.72
IUPAC Name: (S)-2-((R)-2-acetamido-3-(naphthalen-2-yl)propanamido)-N-((S)-1-amino-3-(naphthalen-2-yl)-1-oxopropan-2-yl)-5-guanidinopentanamide
InChIKey: FJFLYSMWSRRMRO-OIFRRMEBSA-N
SMILES: NC([C@H](CC1=CC2=C(C=CC=C2)C=C1)NC([C@H](CCCNC(N)=N)NC([C@H](NC(C)=O)CC3=CC4=C(C=CC=C4)C=C3)=O)=O)=O
Biological Activity: MCL0020 is a potent and selective melanocortin MC4 receptor antagonist, with an IC50 of 11.63 nM. MCL0020 dose-dependently and significantly attenuates restraint stress-induced anorexia without affecting food intake[1].
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MCL0020 | 99.93% | MCL0020 is a potent and selective melanocortin MC4 receptor antagonist, with an IC50 of 11.63 nM. MCL0020 dose-dependently and significantly attenuates restraint stress-induced anorexia without affecting food intake. | ||||||||||||||||||||
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Keywords