479422-22-5
Chemical Structure
CDIBA
- CAS No.: 479422-22-5
- Formula:C31H26ClNO3
- Molecular Weight:496.00
IUPAC Name: 4-(2-(1-benzhydryl-5-chloro-2-methyl-1H-indol-3-yl)ethoxy)benzoic acid
InChIKey: WCJGWNYPOLQBKZ-UHFFFAOYSA-N
SMILES: O=C(O)C1=CC=C(OCCC=2C=3C=C(Cl)C=CC3N(C2C)C(C=4C=CC=CC4)C=5C=CC=CC5)C=C1
Biological Activity: CDIBA is a cytosolic phospholipase A2 (cPLA2) inhibitor. CDIBA inhibits the activation of cPLA2 in rat diaphragm tissue. CDIBA reduces the level of mitochondrial reactive oxygen species in rat diaphragm tissue after prolonged mechanical ventilation. CDIBA attenuates protein degradation, muscle atrophy and decreased muscle strength in the diaphragm of rats after prolonged mechanical ventilation. CDIBA can be used in studies related to ventilator-induced diaphragmatic dysfunction[1].
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CDIBA | CDIBA is a cytosolic phospholipase A2 (cPLA2) inhibitor. CDIBA inhibits the activation of cPLA2 in rat diaphragm tissue. CDIBA reduces the level of mitochondrial reactive oxygen species in rat diaphragm tissue after prolonged mechanical ventilation. CDIBA attenuates protein degradation, muscle atrophy and decreased muscle strength in the diaphragm of rats after prolonged mechanical ventilation. CDIBA can be used in studies related to ventilator-induced diaphragmatic dysfunction. | |||||||||||||||||||||
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Keywords
