494868-78-9
494868-78-9
Chemical Structure
Tafuramycin A
- CAS No.: 494868-78-9
- Formula:C23H21ClN2O6
- Molecular Weight:456.88
InChIKey: DWQYILVVCVQOOR-UHFFFAOYSA-N
SMILES: O=C(N1C2=C(C(C1)CCl)C3=C(C=CO3)C(O)=C2)C4=CC5=C(N4)C(OC)=C(OC)C(OC)=C5
Biological Activity: Tafuramycin A, a Duocarmycin derivative, is a potent anticancer and parasite attenuating agent. Tafuramycin A can be used for triple-negative breast cancer (TNBC) and malaria infection research[1][2].
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Tafuramycin A | Tafuramycin A, a Duocarmycin derivative, is a potent anticancer and parasite attenuating agent. Tafuramycin A can be used for triple-negative breast cancer (TNBC) and malaria infection research. | |||||||||||||||||||||
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References
- [1]. El-Deeb IM, et al. Selective Targeting of Breast Cancer by Tafuramycin A Using SMA-Nanoassemblies. Molecules. 2021 Jun 9;26(12):3532. [Content Brief]
- [2]. El-Deeb IM, et al. A versatile synthesis of "tafuramycin A": a potent anticancer and parasite attenuating agent. Org Biomol Chem. 2014 Jun 28;12(24):4260-4. [Content Brief]
Keywords
