50277-02-6
50277-02-6
Chemical Structure
Parvisoflavone B
- CAS No.: 50277-02-6
- Formula:C20H16O6
- Molecular Weight:352.34
IUPAC Name: 7-(2,4-dihydroxyphenyl)-5-hydroxy-2,2-dimethyl-2H,6H-pyrano[3,2-g]chromen-6-one
InChIKey: YKYNYMQDXOWMDT-UHFFFAOYSA-N
SMILES: O=C1C(=COC2=CC=3OC(C=CC3C(O)=C12)(C)C)C=4C=CC(O)=CC4O
Biological Activity: Parvisoflavone B is a prenylated flavonoid. Parvisoflavone B can be isolated from root bark of Erythrina mildbraedii. Parvisoflavone B inhibits PTP1B activity with an IC50 of 42.6 μM. Parvisoflavone B inhibits α-glucosidase with an IC50 of 12.19 μM. Parvisoflavone B can be used in the research of type 2 diabetes and obesity[1][2].
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Parvisoflavone B | Parvisoflavone B is a prenylated flavonoid. Parvisoflavone B can be isolated from root bark of Erythrina mildbraedii. Parvisoflavone B inhibits PTP1B activity with an IC50 of 42.6 μM. Parvisoflavone B inhibits α-glucosidase with an IC50 of 12.19 μM. Parvisoflavone B can be used in the research of type 2 diabetes and obesity. | |||||||||||||||||||||
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References
- [1]. Jang J, et al. Prenylated flavonoids with PTP1B inhibitory activity from the root bark of Erythrina mildbraedii. Chem Pharm Bull (Tokyo). 2008 Jan;56(1):85-8. [Content Brief]
- [2]. Dendup T, et al. α-Glucosidase inhibitory activities of isoflavanones, isoflavones, and pterocarpans from Mucuna pruriens. Planta Med. 2014 May;80(7):604-8. [Content Brief]
