Parvisoflavone B
Parvisoflavone B is a prenylated flavonoid. Parvisoflavone B can be isolated from root bark of Erythrina mildbraedii. Parvisoflavone B inhibits PTP1B activity with an IC50 of 42.6 μM. Parvisoflavone B inhibits α-glucosidase with an IC50 of 12.19 μM. Parvisoflavone B can be used in the research of type 2 diabetes and obesity.
For research use only. We do not sell to patients.
- CAS No.: 50277-02-6
- Formula: C20H16O6
- Molecular Weight:352.34
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| MDA-MB-231 | EC50 |
16.9 μM
Compound: 16
|
Cytotoxicity against human MDA-MB-231 cells
Cytotoxicity against human MDA-MB-231 cells
|
[PMID: 28112509] |
Chemical Information
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CAS No. 50277-02-6
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Molecular Weight 352.34
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Formula C20H16O6
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SMILES
O=C1C(=COC2=CC=3OC(C=CC3C(O)=C12)(C)C)C=4C=CC(O)=CC4O
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Jang J, et al. Prenylated flavonoids with PTP1B inhibitory activity from the root bark of Erythrina mildbraedii. Chem Pharm Bull (Tokyo). 2008 Jan;56(1):85-8. [Content Brief]
[2]. Dendup T, et al. α-Glucosidase inhibitory activities of isoflavanones, isoflavones, and pterocarpans from Mucuna pruriens. Planta Med. 2014 May;80(7):604-8. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)