51706-40-2
Chemical Structure
Atenolol hydrochloride
Synonym(s): (RS)-Atenolol hydrochloride; Tenormin hydrochloride; ICI 66082 hydrochloride
- CAS No.: 51706-40-2
- Formula:C14H23ClN2O3
- Molecular Weight:302.80
IUPAC Name: 2-(4-(2-hydroxy-3-(isopropylamino)propoxy)phenyl)acetamide hydrochloride
InChIKey: FFDDLJYKJQGSPW-UHFFFAOYSA-N
SMILES: O=C(N)CC1=CC=C(OCC(O)CNC(C)C)C=C1.Cl
Biological Activity: Atenolol hydrochloride is a cardioselective β1-adrenergic receptor blocker, with a Ki of 697 nM at β1-adrenoceptor in guine pig left ventricle membrane. Atenolol hydrochloride can be used for the research of hypertension and angina pectoris[1][2].
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Atenolol hydrochloride | Atenolol hydrochloride is a cardioselective β1-adrenergic receptor blocker, with a Ki of 697 nM at β1-adrenoceptor in guine pig left ventricle membrane. Atenolol hydrochloride can be used for the research of hypertension and angina pectoris. | |||||||||||||||||||||
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- [1]. Heel RC, et al. Atenolol: a review of its pharmacological properties and therapeutic efficacy in angina pectoris and hypertension. Drugs. 1979;17(6):425-460. [Content Brief]
- [2]. Engel G, et al. (+/-)[125Iodo] cyanopindolol, a new ligand for beta-adrenoceptors: identification and quantitation of subclasses of beta-adrenoceptors in guinea pig. Naunyn Schmiedebergs Arch Pharmacol. 1981;317(4):277-285. [Content Brief]
Keywords
