52259-64-0
Chemical Structure
Fagaronine chloride
- CAS No.: 52259-64-0
- Formula:C21H20ClNO4
- Molecular Weight:385.84
IUPAC Name: 2-hydroxy-3,8,9-trimethoxy-5-methylbenzo[c]phenanthridin-5-ium chloride
InChIKey: VVEPUJCLNRDIEQ-UHFFFAOYSA-N
SMILES: C[N+]1=CC2=CC(OC)=C(C=C2C3=C1C4=CC(OC)=C(C=C4C=C3)O)OC.[Cl-]
Biological Activity: Fagaronine chloride is an alkaloid with inhibitory activity against reverse transcriptase and topoisomerase I. Fagaronine chloride can effectively inhibit the reverse transcriptase of RSii tumor virus at a concentration of 6-60 μg/mL. Fagaronine chloride rapidly blocks the synthesis of DNA polymerase by interacting with the template primer. Fagaronine chloride has shown anti-tumor potential, especially in the study of retroviral infection[1].
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Fagaronine chloride | Fagaronine chloride is an alkaloid with inhibitory activity against reverse transcriptase and topoisomerase I. Fagaronine chloride can effectively inhibit the reverse transcriptase of RSii tumor virus at a concentration of 6-60 μg/mL. Fagaronine chloride rapidly blocks the synthesis of DNA polymerase by interacting with the template primer. Fagaronine chloride has shown anti-tumor potential, especially in the study of retroviral infection. | |||||||||||||||||||||
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