52869-18-8
Chemical Structure
SSAA09E3
- CAS No.: 52869-18-8
- Formula:C21H13NO3
- Molecular Weight:327.33
IUPAC Name: N-(9,10-dioxo-9,10-dihydroanthracen-2-yl)benzamide
InChIKey: SIGATAYQAZTAOH-UHFFFAOYSA-N
SMILES: O=C(NC(C=C1C2=O)=CC=C1C(C3=C2C=CC=C3)=O)C4=CC=CC=C4
Biological Activity: SSAA09E3 is a SARS-CoV entry inhibitor that inhibits SARS/HIV pseudotyped virus entry with an EC50 of 9.7 μM in 293T cells and inhibits SARS-CoV infection of Vero cells with an EC50 of 0.15 μM[1][2].
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SSAA09E3 | 99.42% | SSAA09E3 is a SARS-CoV entry inhibitor that inhibits SARS/HIV pseudotyped virus entry with an EC50 of 9.7 μM in 293T cells and inhibits SARS-CoV infection of Vero cells with an EC50 of 0.15 μM. | ||||||||||||||||||||
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- [1]. Ghosh AK, et al. Drug Development and Medicinal Chemistry Efforts toward SARS-Coronavirus and Covid-19 Therapeutics. ChemMedChem. 2020 Jun 4;15(11):907-932. [Content Brief]
- [2]. Adedeji AO, et al. Novel inhibitors of severe acute respiratory syndrome coronavirus entry that act by three distinct mechanisms. J Virol. 2013 Jul;87(14):8017-28. [Content Brief]
Keywords