536714-52-0
536714-52-0
Chemical Structure
Hit20
- CAS No.: 536714-52-0
- Formula:C22H17ClN6O2S2
- Molecular Weight:496.99
InChIKey: SDACPRUKVUJRJY-UHFFFAOYSA-N
SMILES: CCC1=NN=C(S1)NC(CSC2=NC3=C(C(N2C4=CC=C(C=C4)Cl)=O)NC5=CC=CC=C53)=O
Biological Activity: Hit20 is a PI3Kα selective inhibitor, inhibits PI3Kα kinase activity, suppresses PI3Kα phosphorylation. Hit20 suppresses proliferation, colony formation, migration, and invasion of colon cancer cells. Hit20 can be used for the research of colon cancer[1].
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Hit20 | Hit20 is a PI3Kα selective inhibitor, inhibits PI3Kα kinase activity, suppresses PI3Kα phosphorylation. Hit20 suppresses proliferation, colony formation, migration, and invasion of colon cancer cells. Hit20 can be used for the research of colon cancer. | |||||||||||||||||||||
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References
Keywords
