544-35-4
Chemical Structure
Ethyl linoleate
Synonym(s): Linoleic Acid ethyl ester; Mandenol
- CAS No.: 544-35-4
- Formula:C20H36O2
- Molecular Weight:308.50
IUPAC Name: ethyl (9Z,12Z)-octadeca-9,12-dienoate
InChIKey: FMMOOAYVCKXGMF-MURFETPASA-N
SMILES: CCCCC/C=C\C/C=C\CCCCCCCC(OCC)=O
Biological Activity: Ethyl linoleate (Linoleic Acid ethyl ester) is an orally active unsaturated fatty acid. Ethyl linoleate inhibits the Akt/GSK3β/β-catenin signaling pathway and the activation of NF-κB. Ethyl linoleate induces heme oxygenase-1 and inhibits tyrosinase. Ethyl linoleate has whitening and anti-inflammatory effects. Ethyl linoleate promotes compound absorption. Ethyl linoleate has a significant influence on atherosclerosis. Ethyl linoleate is used in the research of inflammatory diseases. Ethyl linoleate can be used in cosmetics[1][2][3][4][5][6]
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Ethyl linoleate | 99.72% | Ethyl linoleate (Linoleic Acid ethyl ester) is an orally active unsaturated fatty acid. Ethyl linoleate inhibits the Akt/GSK3β/β-catenin signaling pathway and the activation of NF-κB. Ethyl linoleate induces heme oxygenase-1 and inhibits tyrosinase. Ethyl linoleate has whitening and anti-inflammatory effects. Ethyl linoleate promotes compound absorption. Ethyl linoleate has a significant influence on atherosclerosis. Ethyl linoleate is used in the research of inflammatory diseases. Ethyl linoleate can be used in cosmetics | ||||||||||||||||||||
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Ethyl linoleate (Standard) | ≥98% | Ethyl linoleate (Standard) is the analytical standard of Ethyl linoleate. This product is intended for research and analytical applications. Ethyl linoleate (Linoleic Acid ethyl ester) inhibit the development of atherosclerotic lesions and the expression of inflammatory mediators. |
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Ethyl linoleate-d11 | Ethyl linoleate-d11 (Linoleic Acid ethyl ester-d11) is deuterium labeled Ethyl linoleate. Ethyl linoleate (Linoleic Acid ethyl ester) inhibit the development of atherosclerotic lesions and the expression of inflammatory mediators. |
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- [1]. Ko GA, et al. Ethyl linoleate inhibits α-MSH-induced melanogenesis through Akt/GSK3β/β-catenin signal pathway. Korean J Physiol Pharmacol. 2018 Jan;22(1):53-61. [Content Brief]
- [2]. Park SY, et al. Ethyl linoleate from garlic attenuates lipopolysaccharide-induced pro-inflammatory cytokine production by inducing heme oxygenase-1 in RAW264.7 cells. Int Immunopharmacol. 2014 Apr;19(2):253-61. [Content Brief]
- [3]. Wu W, et al. Enhanced bioavailability of silymarin by self-microemulsifying drug delivery system. Eur J Pharm Biopharm. 2006 Jul;63(3):288-94. [Content Brief]
- [4]. Zhu JX, et al. Development of self-microemulsifying drug delivery system for oral bioavailability enhancement of berberine hydrochloride. Drug Dev Ind Pharm. 2013 Mar;39(3):499-506. [Content Brief]
- [5]. Osumi Y, et al. Effects of ethyl-linoleate on the atheromatous changes caused by high cholesterol diet in the rabbit. Jpn J Pharmacol. 1966 Mar;16(1):83-91. [Content Brief]
- [6]. Hyun Jung Koo, et al. Chinese yam extracts containing β-sitosterol and ethyl linoleate protect against atherosclerosis in apolipoprotein E-deficient mice and inhibit muscular expression of VCAM-1 in vitro. J Food Sci. 2014 Apr;79(4):H719-29. [Content Brief]
