55-43-6
Chemical Structure
Dibenamine hydrochloride
Synonym(s): N-(2-Chloroethyl)dibenzylamine hydrochloride
- CAS No.: 55-43-6
- Formula:C16H19Cl2N
- Molecular Weight:296.23
IUPAC Name: N,N-dibenzyl-2-chloroethan-1-amine hydrochloride
InChIKey: LZXCEBPGNFLHEQ-UHFFFAOYSA-N
SMILES: ClCCN(CC1=CC=CC=C1)CC2=CC=CC=C2.[H]Cl
Biological Activity: Dibenamine hydrochloride is a competitive and irreversible adrenergic blocking agent and is known to modify the pharmacological effects of epinephrine. Dibenamine hydrochloride cause a significant increase in the rate of destruction of I-epinephrine in the mouse[1][2].
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Dibenamine hydrochloride | 99.32% | Dibenamine hydrochloride is a competitive and irreversible adrenergic blocking agent and is known to modify the pharmacological effects of epinephrine. Dibenamine hydrochloride cause a significant increase in the rate of destruction of I-epinephrine in the mouse. | ||||||||||||||||||||
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References
- [1]. R W SCHAYER, et al. Effect of dibenamine (N-(2-chloroethyl) dibenzylamine) on the metabolism of radioactive epinephrine.J Biol Chem. 1953 May;202(1):39-43. [Content Brief]
- [2]. H M Maling,et al. Nature of the protection against carbon tetrachloride-induced hepatotoxicity produced by pretreatment with dibenamine (N-(2-chloroethyl)dibenzylamine). Biochem Pharmacol. 1974 May 15;23(10):1479-91. [Content Brief]