5570-19-4
Chemical Structure
2-Nitrophenylboronic acid
- CAS No.: 5570-19-4
- Formula:C6H6BNO4
- Molecular Weight:166.93
IUPAC Name: (2-nitrophenyl)boronic acid
InChIKey: SFUIGUOONHIVLG-UHFFFAOYSA-N
SMILES: OB(C1=CC=CC=C1[N+]([O-])=O)O
Biological Activity: 2-Nitrophenylboronic acid is a small-molecule arylboronic acid reagent selective for cysteine residues that mediates nickel (II)-promoted arylation of cysteine thiols. 2-Nitrophenylboronic acid is used in research related to peptide modification and also serves as a substrate for Suzuki-Miyaura coupling reactions in research related to organic synthesis[1][2].
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2-Nitrophenylboronic acid | 99.74% | 2-Nitrophenylboronic acid is a small-molecule arylboronic acid reagent selective for cysteine residues that mediates nickel (II)-promoted arylation of cysteine thiols. 2-Nitrophenylboronic acid is used in research related to peptide modification and also serves as a substrate for Suzuki-Miyaura coupling reactions in research related to organic synthesis. | ||||||||||||||||||||
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References
- [1]. Hyland K T. The Suzuki–Miyaura Cross-Coupling as the Key Step in the Synthesis of 2-Aminobiphenyls and 2,2'-Diaminobiphenyls: Application in the Synthesis of Schiff Base Complexes of Zn. European Journal of Organic Chemistry. 2020;2020(27):4208-4226.
- [2]. Hanaya K, et al. Rapid nickel(ii)-promoted cysteine S-arylation with arylboronic acids. Chemical communications (Cambridge, England). 2019 Feb 28;55(19):2841-2844.