5636-83-9
5636-83-9
Chemical Structure
Dimethindene
- CAS No.: 5636-83-9
- Formula:C20H24N2
- Molecular Weight:292.42
IUPAC Name: N,N-dimethyl-2-(3-(1-(pyridin-2-yl)ethyl)-1H-inden-2-yl)ethan-1-amine
InChIKey: MVMQESMQSYOVGV-UHFFFAOYSA-N
SMILES: CC(C1=C(CCN(C)C)CC2=C1C=CC=C2)C3=NC=CC=C3
Biological Activity: Dimethindene is a potent, selective histamine H1 antagonist. Dimethindene impairs cutaneous wound healing (WH). Dimethindene can block K+ currents[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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Dimethindene | 98.94% | Dimethindene is a potent, selective histamine H1 antagonist. Dimethindene impairs cutaneous wound healing (WH). Dimethindene can block K+ currents. | ||||||||||||||||||||
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References
- [1]. Weller K, et, al. Mast cells are required for normal healing of skin wounds in mice. FASEB J. 2006 Nov;20(13):2366-8. [Content Brief]
- [2]. Sakuta H. Inhibition by histamine H1 receptor antagonists of endogenous glibenclamide-sensitive K+ channels in follicle-enclosed Xenopus oocytes. Eur J Pharmacol. 1994 Jan 1;266(1):99-102. [Content Brief]
