56824-20-5
56824-20-5
Chemical Structure
Amiprilose
Synonym(s): SM1213; Therafectin
- CAS No.: 56824-20-5
- Formula:C14H27NO6
- Molecular Weight:305.37
IUPAC Name: (R)-1-((3aR,5R,6S,6aR)-6-(3-(dimethylamino)propoxy)-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)ethane-1,2-diol
InChIKey: YXBQLONCIPUQKO-UJPOAAIJSA-N
SMILES: O[C@@H]([C@H]1O[C@H]2[C@H](OC(C)(C)O2)[C@H]1OCCCN(C)C)CO
Biological Activity: Amiprilose (SM1213; Therafectin) is a potent inhibitor against Hepatocellular carcinoma (HCC). Amiprilose induces lymphokine-induced macrophage activation directly to kill Listeria monocytogenes[1][2].
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Amiprilose | Amiprilose (SM1213; Therafectin) is a potent inhibitor against Hepatocellular carcinoma (HCC). Amiprilose induces lymphokine-induced macrophage activation directly to kill Listeria monocytogenes. | |||||||||||||||||||||
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References
- [1]. Wang XK, et al. Clinical significance of long non-coding RNA DUXAP8 and its protein coding genes in hepatocellular carcinoma. J Cancer. 2020 Aug 25;11(20):6140-6156. [Content Brief]
- [2]. Hadden JW. Effects of isoprinosine, levamisole, muramyl dipeptide, and SM1213 on lymphocyte and macrophage function in vitro. Cancer Treat Rep. 1978 Nov;62(11):1981-5. [Content Brief]
