Amiprilose
Amiprilose (SM1213; Therafectin) is a potent inhibitor against Hepatocellular carcinoma (HCC). Amiprilose induces lymphokine-induced macrophage activation directly to kill Listeria monocytogenes.
For research use only. We do not sell to patients.
- CAS No.: 56824-20-5
- Formula: C14H27NO6
- Molecular Weight:305.37
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
Chemical Information
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CAS No. 56824-20-5
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Molecular Weight 305.37
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Formula C14H27NO6
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SMILES
O[C@@H]([C@H]1O[C@H]2[C@H](OC(C)(C)O2)[C@H]1OCCCN(C)C)CO
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Synonyms
SM1213; Therafectin
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Liver Cancer Modeling
Liver cancer can be classified into primary liver cancer and secondary liver cancer. Secondary liver cancer is the metastatic liver cancer. Primary liver cancer includes hepatocellular carcinoma (HCC), intrahepatic cholangiocarcinoma (ICC) and fibrolamellar HCC, of which HCC is the most common form, accounting for approximately 90% of primary liver cancers[1]. HCC mouse models include chemical agent-induced models, transplanted tumor models, and genetic engineered models.
Purity & Documentation
References
[1]. Wang XK, et al. Clinical significance of long non-coding RNA DUXAP8 and its protein coding genes in hepatocellular carcinoma. J Cancer. 2020 Aug 25;11(20):6140-6156. [Content Brief]
[2]. Hadden JW. Effects of isoprinosine, levamisole, muramyl dipeptide, and SM1213 on lymphocyte and macrophage function in vitro. Cancer Treat Rep. 1978 Nov;62(11):1981-5. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)