57018-04-9
Chemical Structure
Tolclofos-methyl
- CAS No.: 57018-04-9
- Formula:C9H11Cl2O3PS
- Molecular Weight:301.13
IUPAC Name: O-(2,6-dichloro-4-methylphenyl) O,O-dimethyl phosphorothioate
InChIKey: OBZIQQJJIKNWNO-UHFFFAOYSA-N
SMILES: S=P(OC)(OC1=C(Cl)C=C(C)C=C1Cl)OC
Biological Activity: Tolclofos-methyl is an organophosphorus fungicide. Tolclofos-methyl undergoes photoinduced oxidative degradation to form oxo-analog derivatives. Tolclofos-methyl inhibits spore division in fungi and oomycetes, induces cytoplasmic leakage, and interferes with flagellar movement. Tolclofos-methyl is rapidly metabolized and excreted in rodents. Tolclofos-methyl can be used in studies related to fungal infections[1][2][3].
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Tolclofos-methyl | 98.52% | Tolclofos-methyl is an organophosphorus fungicide. Tolclofos-methyl undergoes photoinduced oxidative degradation to form oxo-analog derivatives. Tolclofos-methyl inhibits spore division in fungi and oomycetes, induces cytoplasmic leakage, and interferes with flagellar movement. Tolclofos-methyl is rapidly metabolized and excreted in rodents. Tolclofos-methyl can be used in studies related to fungal infections. | ||||||||||||||||||||
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Tolclofos-methyl (Standard) | 98.58% | Tolclofos-methyl (Standard) is the analytical standard of Tolclofos-methyl (HY-B2053). This product is intended for research and analytical applications. Tolclofos-methyl is an organophosphorus fungicide. Tolclofos-methyl undergoes photoinduced oxidative degradation to form oxo-analog derivatives. Tolclofos-methyl inhibits spore division in fungi and oomycetes, induces cytoplasmic leakage, and interferes with flagellar movement. Tolclofos-methyl is rapidly metabolized and excreted in rodents. Tolclofos-methyl can be used in studies related to fungal infections. | ||||||||||||||||||||
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References
- [1]. Katagi T. Photoinduced oxidation of the organophosphorus fungicide tolclofos-methyl on clay minerals. J Agric Food Chem. 1990;38:1594-1600.
- [2]. Kato T. Mode of antifungal action of a new fungicide, tolclofos-methyl. In: Mode of Action, Metabolism and Toxicology, Pesticide Chemistry: Human Welfare and the Environment. 1983:153-157.
- [3]. Mihara K, et al. Metabolism of Tolclofos-methyl in Rats and Mice. J Pestic Sci. 1981;6:65-74.
