572-67-8
572-67-8
Chemical Structure
Isoreserpiline
- CAS No.: 572-67-8
- Formula:C23H28N2O5
- Molecular Weight:412.48
InChIKey: FGWJRZQNNZVCHR-HAHWVIBASA-N
SMILES: COC(C1=CO[C@@H](C)[C@]2([H])CN3CCC(C4=CC(OC)=C(OC)C=C4N5)=C5[C@]3([H])C[C@]12[H])=O
Biological Activity: Isoreserpiline is an orally active and BBB-penetrable indole alkaloids with antibacterial and antipsychotic activity. Isoreserpiline is even more effective when used in combination with antibiotics and inhibits the activity of bacterial efflux pumps. Isoreserpiline improves Amphetamine-induced hyperactivity in mice[1][2] .
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Isoreserpiline | Isoreserpiline is an orally active and BBB-penetrable indole alkaloids with antibacterial and antipsychotic activity. Isoreserpiline is even more effective when used in combination with antibiotics and inhibits the activity of bacterial efflux pumps. Isoreserpiline improves Amphetamine-induced hyperactivity in mice . | |||||||||||||||||||||
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References
- [1]. Dwivedi GR, et al. Synergy Potential of Indole Alkaloids and Its Derivative against Drug-resistant Escherichia coli. Chem Biol Drug Des. 2015 Dec;86(6):1471-81. [Content Brief]
- [2]. Gupta S, et al. Bioactivity guided isolation of antipsychotic constituents from the leaves of Rauwolfia tetraphylla L. Fitoterapia. 2012 Sep;83(6):1092-9. [Content Brief]
Keywords
