573951-20-9
573951-20-9
Chemical Structure
15-Deoxy-Δ12,14-prostaglandin A1
- CAS No.: 573951-20-9
- Formula:C20H30O3
- Molecular Weight:318.45
IUPAC Name: 7-((R,Z)-2-((E)-oct-2-en-1-ylidene)-5-oxocyclopent-3-en-1-yl)heptanoic acid
InChIKey: LDOCIRJMPUHXRM-YUJGFSRTSA-N
SMILES: OC(CCCCCC[C@@H]1/C(C=CC1=O)=C\C=C\CCCCC)=O
Biological Activity: 15-Deoxy-Δ12,14-prostaglandin A1 is a deoxyanalog of prostaglandins that inhibits NF-κB signaling and induces apoptosis. 15-Deoxy-Δ12,14-prostaglandin A1 inhibits TNF-α-induced upregulation of inflammatory endothelial cell adhesion molecule (CAM) and avoids monocyte arrest[1].
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15-Deoxy-Δ12,14-prostaglandin A1 | 15-Deoxy-Δ12,14-prostaglandin A1 is a deoxyanalog of prostaglandins that inhibits NF-κB signaling and induces apoptosis. 15-Deoxy-Δ12,14-prostaglandin A1 inhibits TNF-α-induced upregulation of inflammatory endothelial cell adhesion molecule (CAM) and avoids monocyte arrest. | |||||||||||||||||||||
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References
Keywords
