5817-39-0
5817-39-0
Chemical Structure
Reverse T3
Synonym(s): 3′,5′,3-Triiodothyronine
- CAS No.: 5817-39-0
- Formula:C15H12I3NO4
- Molecular Weight:650.97
IUPAC Name: (S)-2-amino-3-(4-(4-hydroxy-3,5-diiodophenoxy)-3-iodophenyl)propanoic acid
InChIKey: HZCBWYNLGPIQRK-LBPRGKRZSA-N
SMILES: IC(C=C(C=C1)C[C@H](N)C(O)=O)=C1OC2=CC(I)=C(C(I)=C2)O
Biological Activity: Reverse T3 is a thyroid hormone that can be generated by deiodination of the prohormone thyroxine[1]. Reverse T3 inhibits the increase of sodium current generated by other thyroid hormone analogs in neonatal rat myocytes[2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Reverse T3 | 96.22% | Reverse T3 is a thyroid hormone that can be generated by deiodination of the prohormone thyroxine. Reverse T3 inhibits the increase of sodium current generated by other thyroid hormone analogs in neonatal rat myocytes. | ||||||||||||||||||||
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Reverse T3 (Standard) | 95.63% | Reverse T3 (Standard) is the analytical standard of Reverse T3. This product is intended for research and analytical applications. Reverse T3 is a thyroid hormone that can be generated by deiodination of the prohormone thyroxine. Reverse T3 inhibits the increase of sodium current generated by other thyroid hormone analogs in neonatal rat myocytes. | ||||||||||||||||||||
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Reverse T3-13C6 hydrochloride | 96% | Reverse T3-13C6 (hydrochloride) is the 13C labeled Reverse T3. | ||||||||||||||||||||
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Reverse T3-13C6 | 3,3',5'-Triiodo-L-thyronine-13C6 is 13C labeled 3,3',5'-Triiodo-L-thyronine. | |||||||||||||||||||||
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References
- [1]. Nicod P, et al. Radioimmunoassay for 3,3',5'-triiodo-L-thyronine in unextracted serum: method and clinical results. J Clin Endocrinol Metab. 1976 May;42(5):823-9. [Content Brief]
- [2]. Rebolledo RA, et al. Anti-Apoptotic Effects of 3,3',5-Triiodo-L-Thyronine in the Liver of Brain-Dead Rats. PLoS One. 2015 Oct 5;10(10):e0138749. [Content Brief]
