594839-88-0
594839-88-0
Chemical Structure
Tafamidis
- CAS No.: 594839-88-0
- Formula:C14H7Cl2NO3
- Molecular Weight:308.12
IUPAC Name: 2-(3,5-dichlorophenyl)benzo[d]oxazole-6-carboxylic acid
InChIKey: TXEIIPDJKFWEEC-UHFFFAOYSA-N
SMILES: O=C(C1=CC=C2N=C(C3=CC(Cl)=CC(Cl)=C3)OC2=C1)O
Biological Activity: Tafamidis is a potent and selective transthyretin (TTR) stabilizer, shows comparable potency and efficacy to the mutumant homotetramers V30M-TTR, V122I-TTR and wild type WT-TTR, with EC50s of 2.7-3.2 μM. Tafamidis inhibits amyloidogenesis[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Tafamidis | 99.93% | Tafamidis is a potent and selective transthyretin (TTR) stabilizer, shows comparable potency and efficacy to the mutumant homotetramers V30M-TTR, V122I-TTR and wild type WT-TTR, with EC50s of 2.7-3.2 μM. Tafamidis inhibits amyloidogenesis. | ||||||||||||||||||||
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Tafamidis (Standard) | 99.24% | Tafamidis (Standard) is the analytical standard of Tafamidis. This product is intended for research and analytical applications. Tafamidis is a potent and selective transthyretin (TTR) stabilizer, shows comparable potency and efficacy to the mutumant homotetramers V30M-TTR, V122I-TTR and wild type WT-TTR, with EC50s of 2.7-3.2 μM. Tafamidis inhibits amyloidogenesis. | ||||||||||||||||||||
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Tafamidis-d3 | Tafamidis-d3 is deuterium labeled Tafamidis. Tafamidis is a potent and selective transthyretin (TTR) stabilizer, shows comparable potency and efficacy to the mutumant homotetramers V30M-TTR, V122I-TTR and wild type WT-TTR, with EC50s of 2.7-3.2 μM. Tafamidis inhibits amyloidogenesis. | |||||||||||||||||||||
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References
