60719-84-8
60719-84-8
Chemical Structure
Amrinone
Synonym(s): Inamrinone
- CAS No.: 60719-84-8
- Formula:C10H9N3O
- Molecular Weight:187.20
IUPAC Name: 5-amino-[3,4'-bipyridin]-6(1H)-one
InChIKey: RNLQIBCLLYYYFJ-UHFFFAOYSA-N
SMILES: O=C1C(N)=CC(C2=CC=NC=C2)=CN1
Biological Activity: Amrinone (Inamrinone) is a positive inotropic-vasodilator agent. Amrinone is a selective phosphodiesterase III inhibitor that increases cyclic adenosine monophosphate by preventing its breakdown. Amrinone is also an orally active, non-glycosidic and non-catecholamine cardiotonic agent[1][2][3].
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Amrinone | 99.93% | Amrinone (Inamrinone) is a positive inotropic-vasodilator agent. Amrinone is a selective phosphodiesterase III inhibitor that increases cyclic adenosine monophosphate by preventing its breakdown. Amrinone is also an orally active, non-glycosidic and non-catecholamine cardiotonic agent. | ||||||||||||||||||||
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Amrinone (Standard) | ≥98% | Amrinone (Standard) is the analytical standard of Amrinone. This product is intended for research and analytical applications. Amrinone (Inamrinone) is a positive inotropic-vasodilator agent. Amrinone is a selective phosphodiesterase III inhibitor that increases cyclic adenosine monophosphate by preventing its breakdown. Amrinone is also an orally active, non-glycosidic and non-catecholamine cardiotonic agent. | ||||||||||||||||||||
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References
- [1]. A A Alousi, et al. The Beneficial Effect of Amrinone on Acute Drug-Induced Heart Failure in the Anaesthetised Dog. Cardiovasc Res. 1985 Aug;19(8):483-94. [Content Brief]
- [2]. S Ichioka, et al. Clinical Use of Amrinone (A Selective Phosphodiesterase III Inhibitor) in Reconstructive Surgery. Plast Reconstr Surg. 2001 Dec;108(7):1931-7. [Content Brief]
- [3]. T H LeJemtel, et al. Amrinone: A New Non-Glycosidic, Non-Adrenergic Cardiotonic Agent Effective in the Treatment of Intractable Myocardial Failure in Man. Circulation. 1979 Jun;59(6):1098-104. [Content Brief]
