60796-64-7
60796-64-7
Chemical Structure
Norbraylin
- CAS No.: 60796-64-7
- Formula:C14H12O4
- Molecular Weight:244.24
IUPAC Name: 6-hydroxy-8,8-dimethyl-2H,8H-pyrano[2,3-f]chromen-2-one
InChIKey: OYPWMLRFDXSKJG-UHFFFAOYSA-N
SMILES: CC1(C=CC2=C(C(O)=CC3=C2OC(C=C3)=O)O1)C
Biological Activity: Norbraylin is a coumarin component and a PDE4 inhibitor with an IC50 of 7.15 μM, which is isolated from the trunk bark of *Cedrelopsis grevei*. Norbraylin is applicable to research related to asthma and chronic obstructive pulmonary disease[1][2].
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Norbraylin | Norbraylin is a coumarin component and a PDE4 inhibitor with an IC50 of 7.15 μM, which is isolated from the trunk bark of *Cedrelopsis grevei*. Norbraylin is applicable to research related to asthma and chronic obstructive pulmonary disease. | |||||||||||||||||||||
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References
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[1]. Chen L, et al. (P)/(M)-corinepalensin A, a pair of axially chiral prenylated bicoumarin enantiomers with a rare C-5C-5' linkage from the twigs of Coriaria nepalensis. Phytochemistry. 2018 May;149:140-145.
[Content Brief] - [2]. Rakotoarison O, et al. Vasorelaxing properties and bio-guided fractionation of Cedrelopsis grevei. Planta medica. 2003 Feb;69(2):179-81. [Content Brief]
