Norbraylin
Norbraylin is a coumarin component and a PDE4 inhibitor with an IC50 of 7.15 μM, which is isolated from the trunk bark of *Cedrelopsis grevei*. Norbraylin is applicable to research related to asthma and chronic obstructive pulmonary disease.
For research use only. We do not sell to patients.
- CAS No.: 60796-64-7
- Formula: C14H12O4
- Molecular Weight:244.24
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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PDE4D2 7.15 μM (IC50) |
Fractions containing Norbraylin mediate vasodilatory effects[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 60796-64-7
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Molecular Weight 244.24
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Formula C14H12O4
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SMILES
CC1(C=CC2=C(C(O)=CC3=C2OC(C=C3)=O)O1)C
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1].
Chen L, et al. (P)/(M)-corinepalensin A, a pair of axially chiral prenylated bicoumarin enantiomers with a rare C-5C-5' linkage from the twigs of Coriaria nepalensis. Phytochemistry. 2018 May;149:140-145.
[Content Brief]
[2]. Rakotoarison O, et al. Vasorelaxing properties and bio-guided fractionation of Cedrelopsis grevei. Planta medica. 2003 Feb;69(2):179-81. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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