612547-11-2
Chemical Structure
PL-100
- CAS No.: 612547-11-2
- Formula:C33H44N4O6S
- Molecular Weight:624.79
IUPAC Name: methyl ((S)-1-(((S)-5-((4-amino-N-isobutylphenyl)sulfonamido)-6-hydroxyhexyl)amino)-1-oxo-3,3-diphenylpropan-2-yl)carbamate
InChIKey: QAHLFXYLXBBCPS-IZEXYCQBSA-N
SMILES: O=S(N(CC(C)C)[C@H](CO)CCCCNC([C@@H](NC(OC)=O)C(C1=CC=CC=C1)C2=CC=CC=C2)=O)(C3=CC=C(C=C3)N)=O
Biological Activity: PL-100 is a potent HIV-1 protease inhibitor with a Ki of 36 pM and an EC50 of 16 nM. PL-100 inhibits viral replication by suppressing HIV-1 protease activity and demonstrates excellent antiviral efficacy against drug-resistant HIV strains. PL-100 can be used in research on drug-resistant HIV disease[1].
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PL-100 | PL-100 is a potent HIV-1 protease inhibitor with a Ki of 36 pM and an EC50 of 16 nM. PL-100 inhibits viral replication by suppressing HIV-1 protease activity and demonstrates excellent antiviral efficacy against drug-resistant HIV strains. PL-100 can be used in research on drug-resistant HIV disease. | |||||||||||||||||||||
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