619-67-0
Chemical Structure
4-Hydrazinobenzoic acid
Synonym(s): p-Hydrazinobenzoic acid
- CAS No.: 619-67-0
- Formula:C7H8N2O2
- Molecular Weight:152.15
IUPAC Name: 4-hydrazinylbenzoic acid
InChIKey: PCNFLKVWBDNNOW-UHFFFAOYSA-N
SMILES: O=C(O)C1=CC=C(NN)C=C1
Biological Activity: 4-Hydrazinobenzoic acid (p-Hydrazinobenzoic acid) is a DNA-damaging agent. 4-Hydrazinobenzoic acid induces copper-dependent oxidative damage, accompanied by strand breaks and base modifications; autoxidation generates hydrogen peroxide and cuprous ion-derived ROS. 4-Hydrazinobenzoic acid is cytotoxic to cancer cells and normal cells. 4-Hydrazinobenzoic acid can be used in cancer research[1][2][3].
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4-Hydrazinobenzoic acid | 99.68% | 4-Hydrazinobenzoic acid (p-Hydrazinobenzoic acid) is a DNA-damaging agent. 4-Hydrazinobenzoic acid induces copper-dependent oxidative damage, accompanied by strand breaks and base modifications; autoxidation generates hydrogen peroxide and cuprous ion-derived ROS. 4-Hydrazinobenzoic acid is cytotoxic to cancer cells and normal cells. 4-Hydrazinobenzoic acid can be used in cancer research. | ||||||||||||||||||||
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4-Hydrazinobenzoic acid (Standard) | ≥98% | 4-Hydrazinobenzoic acid (Standard) (p-Hydrazinobenzoic acid (Standard)) is the analytical standard of 4-Hydrazinobenzoic acid (HY-W017382). This product is intended for research and analytical applications. 4-Hydrazinobenzoic acid (p-Hydrazinobenzoic acid) is a DNA-damaging agent. 4-Hydrazinobenzoic acid induces copper-dependent oxidative damage, accompanied by strand breaks and base modifications; autoxidation generates hydrogen peroxide and cuprous ion-derived ROS. 4-Hydrazinobenzoic acid is cytotoxic to cancer cells and normal cells. 4-Hydrazinobenzoic acid can be used in cancer research. | ||||||||||||||||||||
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Similarity Score 0.87
HY-B10084-Aminobenzoic acid -
Similarity Score 0.85
HY-W0171754-Formamidobenzoic acid -
Similarity Score 0.85
HY-B12584-(Aminomethyl)benzoic acid -
Similarity Score 0.83
HY-W0133964-Iodobenzoic acid -
Similarity Score 0.83
HY-787004-Bromobenzoic acid -
Similarity Score 0.83
HY-41465R4-Chlorobenzoic acid (Standard) -
Similarity Score 0.83
HY-W0136774-Fluorobenzoic acid -
Similarity Score 0.83
HY-Y0264R4-Hydroxybenzoic acid (Standard) -
Similarity Score 0.83
HY-Y0264S4-Hydroxybenzoic acid-13C6 -
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References
- [1]. Abuelizz HA, et al. Exploiting the 4-hydrazinobenzoic acid moiety for the development of anticancer agents: Synthesis and biological profile. Bioorganic chemistry. 2020 Sep;102:104098.
- [2]. Oikawa S, et al. Radical production and DNA damage induced by carcinogenic 4-hydrazinobenzoic acid, an ingredient of mushroom Agaricus bisporus. Free radical research. 2006 Jan;40(1):31-9.
