62265-73-0
62265-73-0
Chemical Structure
KB02
- CAS No.: 62265-73-0
- Formula:C11H12ClNO2
- Molecular Weight:225.67
InChIKey: JYUWHHHXECHQED-UHFFFAOYSA-N
SMILES: OC1=CC=C(N(C(CCl)=O)CCC2)C2=C1
Biological Activity: KB02 is a DCAF16-recruiting ligand that covalently binds to a ligandable cysteine on DCAF16, recruiting the E3 ligase to mediate target protein degradation. KB02 serves as a DCAF16-binding fragment for the synthesis of SHP2 PROTACs[1].
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KB02 | KB02 is a DCAF16-recruiting ligand that covalently binds to a ligandable cysteine on DCAF16, recruiting the E3 ligase to mediate target protein degradation. KB02 serves as a DCAF16-binding fragment for the synthesis of SHP2 PROTACs. | |||||||||||||||||||||
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