63516-07-4
Chemical Structure
Flutropium bromide
Synonym(s): Ba 598Br; Flubron
- CAS No.: 63516-07-4
- Formula:C24H29BrFNO3
- Molecular Weight:478.39
IUPAC Name: (1R,3r,5S,8r)-8-(2-fluoroethyl)-3-(2-hydroxy-2,2-diphenylacetoxy)-8-methyl-8-azabicyclo[3.2.1]octan-8-ium bromide
InChIKey: FNUZASGZEHGWQM-RJRMRWARSA-M
SMILES: FCC[N@@+]([C@@H](CC1)C2)(C)[C@H]1C[C@@H]2OC(C(C3=CC=CC=C3)(C4=CC=CC=C4)O)=O.[Br-]
Biological Activity: Flutropium bromide (Ba 598Br) is a organic bromide salt of flutropium. Flutropium bromide shows an anticholinergic effect. Flutropium bromide effectively suppresses spasms and it can be used for the research of asthma and chronic obstructive pulmonary disease[1][2][3].
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Flutropium bromide | Flutropium bromide (Ba 598Br) is a organic bromide salt of flutropium. Flutropium bromide shows an anticholinergic effect. Flutropium bromide effectively suppresses spasms and it can be used for the research of asthma and chronic obstructive pulmonary disease. | |||||||||||||||||||||
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- [1]. Mizuno H, et al. [Effects of flutropium bromide, a new anti-asthma drug, alone or in combination with salbutamol, aminophylline and disodium cromoglycate on the acetylcholine induced bronchoconstriction]. Nihon Yakurigaku Zasshi. 1990 Jan;95(1):31-40. [Content Brief]
- [2]. Misawa M, et al. [Effects of flutropium bromide, a new antiasthma drug, on mediator release from mast cells and actions of mediators]. Nihon Yakurigaku Zasshi. 1988 Feb;91(2):97-103. Japanese. [Content Brief]
- [3]. Bauer R, Fügner A. Pharmacology of the anticholinergic bronchospasmolytic agent flutropium bromide. Arzneimittelforschung. 1986 Sep;36(9):1348-52. [Content Brief]
Keywords
