64218-02-6
Chemical Structure
Plaunotol
Synonym(s): CS-684
- CAS No.: 64218-02-6
- Formula:C20H34O2
- Molecular Weight:306.48
IUPAC Name: (2Z,6E)-2-((E)-4,8-dimethylnona-3,7-dien-1-yl)-6-methylocta-2,6-diene-1,8-diol
InChIKey: SUWYPNNPLSRNPS-UNTSEYQFSA-N
SMILES: C/C(C)=C\CC/C(C)=C/CC/C(CO)=C/CC/C(C)=C/CO
Biological Activity: Plaunotol is an orally active acyclic diterpene alcohol. Plaunotol has antibacterial activity against Helicobacter pylori which causes peptic ulcer [1]. Plaunotol inhibits tumor angiogenesis and cell proliferation. Plaunotol induces apoptosis by activation of caspase 8 and caspase 9 pathways. Plaunotol is a potential anticancer agent against colon cancer [2].
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Plaunotol | Plaunotol is an orally active acyclic diterpene alcohol. Plaunotol has antibacterial activity against Helicobacter pylori which causes peptic ulcer . Plaunotol inhibits tumor angiogenesis and cell proliferation. Plaunotol induces apoptosis by activation of caspase 8 and caspase 9 pathways. Plaunotol is a potential anticancer agent against colon cancer . | |||||||||||||||||||||
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References
- [1]. S. Songkro, et al. Investigation of plaunoi-loaded micro/nanoemulsions for the treatment of dermatitis: formulation, evaluation and skin irritation studies. J. DRUG DEL. SCI. TECH. 2011 21 (5) 401-410.
- [2]. Oshikawa N, et al. Plaunotol and geranylgeraniol induce caspase-mediated apoptosis in colon cancer. J Surg Res. 2009 May 15;153(2):246-53. [Content Brief]
