645-43-2
645-43-2
Chemical Structure
Guanethidine sulfate
Synonym(s): Guanethidine monosulfate
- CAS. Nr.: 645-43-2
- Formula:C10H24N4O4S
- Molecular Weight:296.39
IUPAC Name: 1-(2-(azocan-1-yl)ethyl)guanidine sulfate
InChIKey: YUFWAVFNITUSHI-UHFFFAOYSA-N
SMILES: NC(NCCN1CCCCCCC1)=N.O=S(O)(O)=O
Biological Activity: Guanethidine sulfate (Guanethidine monosulfate), an antihypertensive agent, is an adrenergic neurone blocking agent. Guanethidine sulfate enters noradrenergic nerve terminals by the neuronal amine carrier[1][2].
| Art. -Nr. | Produktname | Reinheit | Beschreibung | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Guanethidine sulfate | 98.0% | Guanethidine sulfate (Guanethidine monosulfate), an antihypertensive agent, is an adrenergic neurone blocking agent. Guanethidine sulfate enters noradrenergic nerve terminals by the neuronal amine carrier. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Guanethidine sulfate (Standard) | ≥98% | Guanethidine (sulfate) (Standard) is the analytical standard of Guanethidine (sulfate). This product is intended for research and analytical applications. Guanethidine sulfate (Guanethidine monosulfate), an antihypertensive agent, is an adrenergic neurone blocking agent. Guanethidine sulfate enters noradrenergic nerve terminals by the neuronal amine carrier. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Arcaine sulfate | 98.0% | Arcaine (sulfate) is a glutamate NMDA receptor inhibitor. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Synthalin A sulfate | Synthalin A sulfate is a biguanylated diamine with antibacterial and hypoglycemic properties. Synthalin A sulfate against S. aureus with a MIC of 64 μg/mL. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
GC7 Sulfate (Standard) | GC7 Sulfate (Standard) is the analytical standard of GC7 Sulfate (HY-108314A). This product is intended for research and analytical applications. GC7 Sulfate is a deoxyhypusine synthase (DHPS) inhibitor. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Esaprazole | 98.06% | Esaprazole (Hexaprazole) is an antiulcer agent that has the effect of promoting the healing of peptic ulcer. Esaprazole can inhibit the secretion of gastric acid and pepsin. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Cyclo(Arg-Pro) | 98.07% | Cyclo(Arg-Pro) (Cyclo(Pro-Arg)) is an inhibitor for chitinase. Cyclo(Arg-Pro) inhibits cell separation of Saccharomyces cerevisiae, without affecting its growth. Cyclo(Arg-Pro) inhibits the morphological change of Candida albicans from yeast form to filamentous form. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Cyclo(Pro-dArg) | Cyclo(Pro-dArg) is an inhibitor of chitinase. Cyclo(Pro-dArg) inhibits the cell separation of Saccharomyces cerevisiae but does not affect its growth. Cyclo(Pro-dArg) inhibits the transition of Candida albicans from yeast to filamentous morphology. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Pramiracetam sulfate | Pramiracetam (CI-879) sulfate Pramiracetam is a PREP (prolyl endopeptidase) inhibitor. Pramiracetam sulfate improves cognitive impairment caused by traumatic brain injury. Pramiracetam sulfate can be used in the study of neurodegenerative diseases. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
3,3'-Piperazine-1,4-diyldipropanoic acid | 3,3'-(Piperazine-1,4-diyl)dipropanoic acid is a PROTAC linker that can be used in the synthesis of PROTACs. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
PIPBS | PIPBS is a zwitterionic buffering agent that is broadly used in cell culture medium. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
1,1'-(Azodicarbonyl)-dipiperidine | 97.0% | 1,1'-(Azodicarbonyl)-dipiperidine (ADDP; SR 4077) is an oxidizing reagent for intracellular reducing agents and a chemical coupling reagent. 1,1'-(Azodicarbonyl)-dipiperidine exhibits biological activities such as pro-oxidation, radiosensitization, and induction of apoptosis, and can serve as a Mitsunobu reaction catalyst for chemical synthesis. 1,1'-(Azodicarbonyl)-dipiperidine oxidizes and depletes intracellular reducing pools such as GSH, leading to protein thiol oxidation and oxidative stress, thereby inhibiting DNA single-strand break repair or altering membrane function, ultimately mediating apoptosis signaling and increasing radiosensitivity. 1,1'-(Azodicarbonyl)-dipiperidine can be used in research on pulmonary arterial hypertension, lymphoma, and teratocarcinoma. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
- [1]. Mitchell JR, et al. Antagonism of the antihypertensive action of guanethidine sulfate by desipramine hydrochloride. JAMA. 1967 Dec 4;202(10):973-6. [Content Brief]
- [2]. Nielsen GD. Guanethidine induced sympathectomy in the adult rat. I. Functional effects following subacute administration. Acta Pharmacol Toxicol (Copenh). 1977 Sep;41(3):203-8. [Content Brief]
