648926-15-2
Chemical Structure
Glycogen phosphorylase-IN-1
- CAS No.: 648926-15-2
- Formula:C17H15ClF2N4O4
- Molecular Weight:412.78
IUPAC Name: 2-chloro-4,5-difluoro-N-((2-methoxy-5-(3-methylureido)phenyl)carbamoyl)benzamide
InChIKey: ROJNYKZWTOHRNU-UHFFFAOYSA-N
SMILES: O=C(NC(NC1=CC(NC(NC)=O)=CC=C1OC)=O)C2=CC(F)=C(F)C=C2Cl
Biological Activity: Glycogen phosphorylase-IN-1 (Compound 42) is an inhibitor for human liver glycogen phosphorylase (hlGPa) and hepatocyte glycogen-derived glucose production with IC50s of 53 and 380 nM, respectively. Glycogen phosphorylase-IN-1 reveals efficacy towards type 2 diabetes[1].
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Glycogen phosphorylase-IN-1 | 98.15% | Glycogen phosphorylase-IN-1 (Compound 42) is an inhibitor for human liver glycogen phosphorylase (hlGPa) and hepatocyte glycogen-derived glucose production with IC50s of 53 and 380 nM, respectively. Glycogen phosphorylase-IN-1 reveals efficacy towards type 2 diabetes. | ||||||||||||||||||||
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Keywords