64917-82-4
64917-82-4
Chemical Structure
Schisantherin D
- CAS No.: 64917-82-4
- Formula:C29H28O9
- Molecular Weight:520.53
InChIKey: PGEJVRVFUGSAJF-SSEZWIOCSA-N
SMILES: COC1=C(C([C@@H]([C@@](O)2C)OC(C3=CC=CC=C3)=O)=CC4=C1OCO4)C(C(C[C@@H]2C)=CC5=C6OCO5)=C6OC
Biological Activity: Schisantherin D is a lignan. Schisantherin D can be isolated from Kadsura interior. Schisantherin D downregulates the expression of ETBR and inhibits the secretion of ECM and ET-1. Schisantherin D alleviates EtOH + ET-1-induced hepatocyte cytotoxicity. Schisantherin D potently inhibits HIV replication in cells[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Schisantherin D | 99.66% | Schisantherin D is a lignan. Schisantherin D can be isolated from Kadsura interior. Schisantherin D downregulates the expression of ETBR and inhibits the secretion of ECM and ET-1. Schisantherin D alleviates EtOH + ET-1-induced hepatocyte cytotoxicity. Schisantherin D potently inhibits HIV replication in cells. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.85
HY-N0858Gomisin G -
Similarity Score 0.85
HY-N0694RSchisantherin A (Standard) -
Similarity Score 0.85
HY-N2988Schisanwilsonin C -
Similarity Score 0.85
HY-N2988ABenzoylgomisin P -
Similarity Score 0.84
HY-N6849InteriotherinA -
Similarity Score 0.73
HY-N0860Schisantherin E -
Similarity Score 0.73
HY-N17298Schisanwilsonin G -
Similarity Score 0.72
HY-N2266Benzoylgomisin O -
Similarity Score 0.72
HY-N12706Heilaohuguosu G -
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References
- [1]. Xu JB, et al. Lignans from Schisandra chinensis ameliorate alcohol and CCl4-induced long-term liver injury and reduce hepatocellular degeneration via blocking ETBR. J Ethnopharmacol. 2020;258:112813. [Content Brief]
- [2]. Chen DF, et al. Two new lignans, interiotherins A and B, as anti-HIV principles from Kadsura interior. J Nat Prod. 1996;59(11):1066-1068. [Content Brief]
