656831-19-5
656831-19-5
Chemical Structure
Ste2Cys
- CAS No.: 656831-19-5
- Formula:C42H81NO6S
- Molecular Weight:728.16
InChIKey: RTQYRFNRSGPMSH-RVFUZGKFSA-N
SMILES: CCCCCCCCCCCCCCCCCC(OC(CSC[C@H](N)C(O)=O)COC(CCCCCCCCCCCCCCCCC)=O)=O
Biological Activity: Ste2Cys is a diacylglycerol cysteine-type immunologic adjuvant lipid molecule. Ste2Cys can bind to TLR2 and activate NF-κB signaling pathway. Ste2Cy can upregulate the expression of MHC II class molecules on the surface of mouse bone marrow-derived D1 dendritic cells. Ste2Cys can be used for research of the development of immunologic vaccines[1][2].
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Ste2Cys | Ste2Cys is a diacylglycerol cysteine-type immunologic adjuvant lipid molecule. Ste2Cys can bind to TLR2 and activate NF-κB signaling pathway. Ste2Cy can upregulate the expression of MHC II class molecules on the surface of mouse bone marrow-derived D1 dendritic cells. Ste2Cys can be used for research of the development of immunologic vaccines. | |||||||||||||||||||||
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References
- [1]. Chua BY, et al. Comparison of lipopeptide-based immunocontraceptive vaccines containing different lipid groups. Vaccine. 2007 Jan 2;25(1):92-101. doi: 10.1016/j.vaccine.2006.07.012IF: 3.5 Q2 . Epub 2006 Jul 31. [Content Brief]
- [2]. Hannah H. Alphs, et al. Multi- component l2 vaccine for prevention of human papillomavirus infection. WO2009059328A2
