65914-84-3
65914-84-3
Chemical Structure
1-Stearoyl-2-arachidonoyl-sn-glycerol
- CAS No.: 65914-84-3
- Formula:C41H72O5
- Molecular Weight:645.01
IUPAC Name: (S)-1-hydroxy-3-(stearoyloxy)propan-2-yl (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate
InChIKey: NSXLMTYRMFVYNT-IUJDHQGTSA-N
SMILES: CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(O[C@@H](CO)COC(CCCCCCCCCCCCCCCCC)=O)=O
Biological Activity: 1-Stearoyl-2-arachidonoyl-sn-glycerol is a diacylglycerol (DAG) containing polyunsaturated fatty acids. 1-Stearoyl-2-arachidonoyl-sn-glycerol can activate PKC. 1-Stearoyl-2-arachidonoyl-sn-glycerol also can augment nonselective cation channel (NSCC) activity[1][2].
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1-Stearoyl-2-arachidonoyl-sn-glycerol | 99.0% | 1-Stearoyl-2-arachidonoyl-sn-glycerol is a diacylglycerol (DAG) containing polyunsaturated fatty acids. 1-Stearoyl-2-arachidonoyl-sn-glycerol can activate PKC. 1-Stearoyl-2-arachidonoyl-sn-glycerol also can augment nonselective cation channel (NSCC) activity. | ||||||||||||||||||||
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1-Stearoyl-2-Arachidonoyl-d8-sn-Glycerol | 1-Stearoyl-2-Arachidonoyl-d8-sn-Glycerol is the deuterium labeled 1-Stearoyl-2-arachidonoyl-sn-glycerol. 1-Stearoyl-2-arachidonoyl-sn-glycerol is a diacylglycerol (DAG) containing polyunsaturated fatty acids. 1-Stearoyl-2-arachidonoyl-sn-glycerol can activate PKC. 1-Stearoyl-2-arachidonoyl-sn-glycerol also can augment nonselective cation channel (NSCC) activity. | |||||||||||||||||||||
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References
- [1]. Song T, et, al. Inositol 1,4,5-trisphosphate activates TRPC3 channels to cause extracellular Ca2+ influx in airway smooth muscle cells. Am J Physiol Lung Cell Mol Physiol. 2015 Dec 15;309(12):L1455-66. [Content Brief]
- [2]. Madani S, et, al. Implication of acyl chain of diacylglycerols in activation of different isoforms of protein kinase C. FASEB J. 2001 Dec;15(14):2595-601. [Content Brief]
