1-Stearoyl-2-arachidonoyl-sn-glycerol
Based on 1 publication(s) in Google Scholar
1-Stearoyl-2-arachidonoyl-sn-glycerol is a diacylglycerol (DAG) containing polyunsaturated fatty acids. 1-Stearoyl-2-arachidonoyl-sn-glycerol can activate PKC. 1-Stearoyl-2-arachidonoyl-sn-glycerol also can augment nonselective cation channel (NSCC) activity.
For research use only. We do not sell to patients.
- Purity : 99.0%
- CAS No.: 65914-84-3
- Formula: C41H72O5
- Molecular Weight:645.01
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Storage:
Solution, -20°C, 2 years
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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Publications Citing Use of MedChemExpress (MCE) 1-Stearoyl-2-arachidonoyl-sn-glycerol
MoreAll Endogenous Metabolite Isoforms
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Biological Activity
Description
IC50 & Target
PKC[2]
In Vitro
1-Stearoyl-2-arachidonoyl-sn-glycerol (0.3-3 μM) augments nonselective cation channel (NSCC) activity in airway smooth muscle cells[1].
1-Stearoyl-2-arachidonoyl-sn-glycerol (0-5 μM) exerts significantly stimulatory effects on activation of PKCα, PKCδ, PKCγ, PKCε and PKCβI[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 65914-84-3
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Appearance Liquid
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Molecular Weight 645.01
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Formula C41H72O5
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Color Colorless to light yellow
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SMILES
CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(O[C@@H](CO)COC(CCCCCCCCCCCCCCCCC)=O)=O
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Solution, -20°C, 2 years
Publications (1)
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Journal Impact Factor
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Most Recent
Purity & Documentation
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Data Sheet (268 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Song T, et, al. Inositol 1,4,5-trisphosphate activates TRPC3 channels to cause extracellular Ca2+ influx in airway smooth muscle cells. Am J Physiol Lung Cell Mol Physiol. 2015 Dec 15;309(12):L1455-66. [Content Brief]
[2]. Madani S, et, al. Implication of acyl chain of diacylglycerols in activation of different isoforms of protein kinase C. FASEB J. 2001 Dec;15(14):2595-601. [Content Brief]
[3]. Glasmacher S, et, al. Characterization of pepcan-23 as pro-peptide of RVD-hemopressin (pepcan-12) and stability of hemopressins in mice. Adv Biol Regul. 2021 May;80:100808. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
1-Stearoyl-2-arachidonoyl-sn-glycerol Related Classifications
HY-131897 Related Classifications
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