1-Stearoyl-2-arachidonoyl-sn-glycerol

Cat. No.: HY-131897 Purity: ≥99.0%: FAQs
Data Sheet SDS COA Handling Instructions

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1-Stearoyl-2-arachidonoyl-sn-glycerol is a diacylglycerol (DAG) containing polyunsaturated fatty acids. 1-Stearoyl-2-arachidonoyl-sn-glycerol can activate PKC. 1-Stearoyl-2-arachidonoyl-sn-glycerol also can augment nonselective cation channel (NSCC) activity.

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1-Stearoyl-2-arachidonoyl-sn-glycerol Chemical Structure

CAS No. : 65914-84-3

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5 mg (15.50 mM * 500 μL in Methyl acetate)	USD 440	In-stock	Estimated Time of Arrival: December 31

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Based on 1 publication(s) in Google Scholar

Other Forms of 1-Stearoyl-2-arachidonoyl-sn-glycerol:

1-Stearoyl-2-Arachidonoyl-d₈-sn-Glycerol Get quote

1 Publications Citing Use of MCE 1-Stearoyl-2-arachidonoyl-sn-glycerol

•Environ Toxicol Pharmacol. 2023 Jun 7;104172. [Abstract]

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•Related Small Molecules:

•Related Proteins:

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PKC PKCα PKCβ PKCγ PKCδ PKCε PKCη PKCζ PKCθ PKCμ PKCι

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TRPC TRPM TRPV TRPA TRPML

Biological Activity
Purity & Documentation
References
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Description	1-Stearoyl-2-arachidonoyl-sn-glycerol is a diacylglycerol (DAG) containing polyunsaturated fatty acids. 1-Stearoyl-2-arachidonoyl-sn-glycerol can activate PKC. 1-Stearoyl-2-arachidonoyl-sn-glycerol also can augment nonselective cation channel (NSCC) activity^[1]^[2].
IC₅₀ & Target	PKC^[2]
In Vitro	1-Stearoyl-2-arachidonoyl-sn-glycerol (0.3-3 μM) augments nonselective cation channel (NSCC) activity in airway smooth muscle cells^[1]. ? 1-Stearoyl-2-arachidonoyl-sn-glycerol (0-5 μM) exerts significantly stimulatory effects on activation of PKCα, PKCδ, PKCγ, PKCε and PKCβI^[2]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. 1-Stearoyl-2-arachidonoyl-sn-glycerol Related Antibodies
Molecular Weight	645.01
Formula	C₄₁H₇₂O₅
CAS No.	65914-84-3
Appearance	Liquid
Color	Colorless to light yellow
SMILES	CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(O[C@@H](CO)COC(CCCCCCCCCCCCCCCCC)=O)=O
Structure Classification	Others
Initial Source	Endogenous metabolite
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Solution, -20°C, 2 years
Purity & Documentation	Purity: ≥99.0% Select Batch: Data Sheet (269 KB) SDS (251 KB) COA (241 KB) Handling Instructions (2659 KB)
References	[1]. Song T, et, al. Inositol 1,4,5-trisphosphate activates TRPC3 channels to cause extracellular Ca2+ influx in airway smooth muscle cells. Am J Physiol Lung Cell Mol Physiol. 2015 Dec 15;309(12):L1455-66. [Content Brief] [2]. Madani S, et, al. Implication of acyl chain of diacylglycerols in activation of different isoforms of protein kinase C. FASEB J. 2001 Dec;15(14):2595-601. [Content Brief] [3]. Glasmacher S, et, al. Characterization of pepcan-23 as pro-peptide of RVD-hemopressin (pepcan-12) and stability of hemopressins in mice. Adv Biol Regul. 2021 May;80:100808. [Content Brief]