66081-37-6
Chemical Structure
Tunicamycin A1
Synonym(s): Tunicamycin 14:1; Tunicamycin II; Tunicamycin C
- CAS No.: 66081-37-6
- Formula:C37H60N4O16
- Molecular Weight:816.89
IUPAC Name: (E)-N-((2S,3R,4R,5R,6R)-2-(((2R,3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-6-((R)-2-((2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)-2-hydroxyethyl)-4,5-dihydroxytetrahydro-2H-pyran-3-yl)-12-methyltridec-2-enamide
InChIKey: YJQCOFNZVFGCAF-LLXUUZRASA-N
SMILES: O[C@@H]1[C@H](O)[C@@H]([C@H](O)C[C@@H](O2)[C@H](O)[C@H](O)[C@@H](NC(/C=C/CCCCCCCCC(C)C)=O)[C@]2([H])O[C@@H](O[C@@H]([C@H]([C@@H]3O)O)CO)[C@@H]3NC(C)=O)O[C@H]1N4C=CC(NC4=O)=O
Biological Activity: Tunicamycin A1 (Tunicamycin 14:1; Tunicamycin II; Tunicamycin C) is an antibiotic. Tunicamycin A1 exhibits antibacterial activity against a variety of bacterial. Tunicamycin A1 can be used in studies related to bacterial infections[1][2].
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Tunicamycin A1 | Tunicamycin A1 (Tunicamycin 14:1; Tunicamycin II; Tunicamycin C) is an antibiotic. Tunicamycin A1 exhibits antibacterial activity against a variety of bacterial. Tunicamycin A1 can be used in studies related to bacterial infections. | |||||||||||||||||||||
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- [1]. Hering J, et al. Exploring the Active Site of the Antibacterial Target MraY by Modified Tunicamycins. ACS Chem Biol. 2020;15(11):2885-2895. [Content Brief]
- [2]. Zhang S, et al. Antimicrobial tunicamycin derivatives from the deep sea-derived Streptomyces xinghaiensis SCSIO S15077. Nat Prod Res. 2020 Jun;34(11):1499-1504. [Content Brief]
Keywords
