66104-23-2
Chemical Structure
Pergolide mesylate
Synonym(s): Pergolide methanesulfonate; LY127809
- CAS No.: 66104-23-2
- Formula:C20H30N2O3S2
- Molecular Weight:410.59
IUPAC Name: (6aR,9R,10aR)-9-((methylthio)methyl)-7-propyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinoline methanesulfonate
InChIKey: UWCVGPLTGZWHGS-ZORIOUSZSA-N
SMILES: [H][C@@]1(N(CCC)C[C@H](CSC)C[C@@]12[H])CC3=CNC4=CC=CC2=C43.CS(=O)(O)=O
Biological Activity: Pergolide mesylate (Pergolide methanesulfonate), an Ergoline derivative, is a potent and orally active dopamine D1 and D2 receptors agonist. Pergolide mesylate can be used for Parkinson's disease and hyperprolactinaemia research[1][2].
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Pergolide mesylate | 99.98% | Pergolide mesylate (Pergolide methanesulfonate), an Ergoline derivative, is a potent and orally active dopamine D1 and D2 receptors agonist. Pergolide mesylate can be used for Parkinson's disease and hyperprolactinaemia research. | ||||||||||||||||||||
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Pergolide mesylate (Standard) | ≥98% | Pergolide (mesylate) (Standard) is the analytical standard of Pergolide (mesylate). This product is intended for research and analytical applications. Pergolide mesylate (Pergolide methanesulfonate), an Ergoline derivative, is a potent and orally active dopamine D1 and D2 receptors agonist. Pergolide mesylate can be used for Parkinson's disease and hyperprolactinaemia research. | ||||||||||||||||||||
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Pergolide-d7 mesylate | Pergolide-d7 (mesylate) is the deuterium labeled Pergolide mesylate. Pergolide mesylate (Pergolide methanesulfonate), an Ergoline derivative, is a potent and orally active dopamine D1 and D2 receptors agonist. Pergolide mesylate can be used for Parkinson's disease and hyperprolactinaemia research. | |||||||||||||||||||||
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Similarity Score 0.91
HY-13720Pergolide -
Similarity Score 0.86
HY-137306Pergolide sulfone -
Similarity Score 0.78
HY-119140LY 116467 -
Similarity Score 0.71
HY-106646CQP-201403 -
Similarity Score 0.69
HY-106465Proterguride -
Similarity Score 0.65
HY-106512Cianergoline -
Similarity Score 0.65
HY-119997Disulergine -
Similarity Score 0.64
HY-W422431Dihydrolysergic acid -
Similarity Score 0.63
HY-12714TDHL -
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References
- [1]. S Franks, et al. Effectiveness of pergolide mesylate in long term treatment of hyperprolactinaemia. Br Med J (Clin Res Ed). 1983 Apr 9;286(6372):1177-9. [Content Brief]
- [2]. Daniela Uberti, et al. Pergolide protects SH-SY5Y cells against neurodegeneration induced by H(2)O(2). Eur J Pharmacol. 2002 Jan 2;434(1-2):17-20. [Content Brief]
