670270-31-2
670270-31-2
Chemical Structure
IU1-47
- No. CAS: 670270-31-2
- Formula:C19H23ClN2O
- Molecular Weight:330.85
IUPAC Name: 1-(1-(4-chlorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl)-2-(piperidin-1-yl)ethan-1-one
InChIKey: VXQIPRWKLACSKZ-UHFFFAOYSA-N
SMILES: CC1=CC(C(CN2CCCCC2)=O)=C(N1C3=CC=C(C=C3)Cl)C
Biological Activity: IU1-47 is a potent and specific USP14 inhibitor with an IC50 of 0.6 μM. IU1-47 inhibits IsoT/USP5 with an IC50 of 20 μM. IU1-47 induces tau elimination in cultured neurons[1].
| Referencia número | Nombre del producto | Pureza | Descripciòn | Pricing | |||||||||||||||||||
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IU1-47 | 99.87% | IU1-47 is a potent and specific USP14 inhibitor with an IC50 of 0.6 μM. IU1-47 inhibits IsoT/USP5 with an IC50 of 20 μM. IU1-47 induces tau elimination in cultured neurons. | ||||||||||||||||||||
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Structural Analogs
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Similarity Score 0.88
HY-13817IU1 -
Similarity Score 0.74
HY-122885IU1-248 -
Similarity Score 0.69
HY-146555Antitubercular agent-14 -
Similarity Score 0.68
HY-W173220Clopirac -
Similarity Score 0.64
HY-W217676SARS-CoV-2 Mpro-IN-58 -
Similarity Score 0.59
HY-111292CYM-5482 -
Similarity Score 0.56
HY-156061NAP-1 -
Similarity Score 0.56
HY-180576Nurr1/RXR agonist 1 -
Similarity Score 0.55
HY-B1139RTolperisone hydrochloride (Standard) -
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