67667-64-5
Chemical Structure
Isozaluzanin C
Synonym(s): Dehydrozaluzanin C-derivative
- CAS No.: 67667-64-5
- Formula:C15H18O3
- Molecular Weight:246.30
IUPAC Name: (3aS,6aR,8R,9aR,9bS)-8-hydroxy-3,6,9-trimethylenedecahydroazuleno[4,5-b]furan-2(3H)-one
InChIKey: XFVLNEYIZGZDHP-HPCHECBXSA-N
SMILES: O=C(O[C@@]([C@@]1([H])C([C@H](O)C[C@@]21[H])=C)([H])[C@@]3([H])CCC2=C)C3=C
Biological Activity: Isozaluzanin C (Dehydrozaluzanin c-derivative) is an anti-inflammatory agent that can be isolated from Saussurea lappa and has immunomodulatory effects. Isozaluzanin C improves tissue damage (lung, kidney, and liver) and excessive inflammation in mice induced by LPS (HY-D1056) or CRKP infection. Isozaluzanin C can be used in the study of bacterial infections and sepsi[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Isozaluzanin C | 96.18% | Isozaluzanin C (Dehydrozaluzanin c-derivative) is an anti-inflammatory agent that can be isolated from Saussurea lappa and has immunomodulatory effects. Isozaluzanin C improves tissue damage (lung, kidney, and liver) and excessive inflammation in mice induced by LPS (HY-D1056) or CRKP infection. Isozaluzanin C can be used in the study of bacterial infections and sepsi. | ||||||||||||||||||||
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References
- [1]. Kalsi S,et al. Isodehydrocostus lactone and isozaluzanin C, two guaianolides from Saussurea lappa[J]. Phytochemistry, 1983, 22(9): 1993-1995.
- [2]. Zou, et al. Dehydrozaluzanin C-derivative protects septic mice by alleviating over-activated inflammatory response and promotes the phagocytosis of macrophages[J]. bioRxiv, 2023: 2023.11. 01.565192.
