682794-85-0
682794-85-0
Chemical Structure
AP-C4
- CAS No.: 682794-85-0
- Formula:C22H20N4O2
- Molecular Weight:372.42
IUPAC Name: N-(2-(1H-indol-3-yl)ethyl)-4-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)pyrimidin-2-amine
InChIKey: KSKZEYZWDRZQFK-UHFFFAOYSA-N
SMILES: C1(C2=CC3=C(OCCO3)C=C2)=NC(NCCC4=CNC5=C4C=CC=C5)=NC=C1
Biological Activity: AP-C4 is an inhibitor of guanosine 3′,5′-cyclic monophosphate (cGMP)-dependent protein kinase II (cGKII) with a pIC50 of 5.2. AP-C3 does not inhibit cGKII-dependent anion secretion[1].
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AP-C4 | AP-C4 is an inhibitor of guanosine 3′,5′-cyclic monophosphate (cGMP)-dependent protein kinase II (cGKII) with a pIC50 of 5.2. AP-C3 does not inhibit cGKII-dependent anion secretion. | |||||||||||||||||||||
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References
Keywords
