68341-09-3
68341-09-3
Chemical Structure
CuATSM
- CAS 番号: 68341-09-3
- Formula:C8H14CuN6S2
- Molecular Weight:321.91
InChIKey: OGNJXAUDXXZGCW-UHFFFAOYSA-L
SMILES: CC1=[N]2[N-]C(NC)=[S][Cu+2]32[S]=C(NC)[N-][N]3=C1C
Biological Activity: CuATSM is a copper complex that scavenges free radicals, inhibits lipid peroxidation and ferroptosis. CuATSM exhibits antioxidant, anti-inflammatory and neuroprotective activities[1][2].
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CuATSM | 99.13% | CuATSM is a copper complex that scavenges free radicals, inhibits lipid peroxidation and ferroptosis. CuATSM exhibits antioxidant, anti-inflammatory and neuroprotective activities. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.53
HY-139826CuATSP -
Similarity Score 0.41
HY-185401ATSM -
Similarity Score 0.41
HY-185401A(E,E)-ATSM -
Similarity Score 0.41
HY-122356Ambazone monohydrate -
Similarity Score 0.41
HY-122356AAmbazone -
Similarity Score 0.40
HY-116767BLT-1 -
Similarity Score 0.40
HY-W034566Hexacyclen -
Similarity Score 0.39
HY-100534IDE 2 -
Similarity Score 0.39
HY-W034576Hexacyclen hexahydrochloride -
Explore the MedChemAI to find more analogs
References
- [1]. Zilka O, et al. Radical-Trapping Antioxidant Activity of Copper and Nickel Bis(Thiosemicarbazone) Complexes Underlies Their Potency as Inhibitors of Ferroptotic Cell Death. J Am Chem Soc. 2021 Nov 17;143(45):19043-19057. [Content Brief]
- [2]. Shi X, et al., Neuroprotective effect of CuATSM in mice stroke model by ameliorating oxidative stress. Neurosci Res. 2021 May;166:55-61. [Content Brief]
