684276-17-3
684276-17-3
Chemical Structure
L-2286
- CAS No.: 684276-17-3
- Formula:C15H19N3OS
- Molecular Weight:289.40
IUPAC Name: 2-((2-(piperidin-1-yl)ethyl)thio)quinazolin-4(3H)-one
InChIKey: QEAAIHDHSHTGMZ-UHFFFAOYSA-N
SMILES: O=C1NC(SCCN2CCCCC2)=NC3=C1C=CC=C3
Biological Activity: L-2286 is an orally active PARP-1 inhibitor. L-2286 alleviates carotid artery remodeling, oxidative stress and inflammation in spontaneously hypertensive rats, protects neurons in the dorsal hippocampus, and reduces pyramidal cell loss and gliosis without affecting blood pressure. L-2286 can be used in research related to hypertension[1].
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L-2286 | L-2286 is an orally active PARP-1 inhibitor. L-2286 alleviates carotid artery remodeling, oxidative stress and inflammation in spontaneously hypertensive rats, protects neurons in the dorsal hippocampus, and reduces pyramidal cell loss and gliosis without affecting blood pressure. L-2286 can be used in research related to hypertension. | |||||||||||||||||||||
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References
Keywords
