694522-87-7
694522-87-7
Chemical Structure
(E/Z)-GO289
- CAS No.: 694522-87-7
- Formula:C17H15BrN4O2S
- Molecular Weight:419.30
IUPAC Name: (E)-5-bromo-2-methoxy-4-(((3-(methylthio)-5-phenyl-4H-1,2,4-triazol-4-yl)imino)methyl)phenol
InChIKey: DARDDBZKGVEVKB-VXLYETTFSA-N
SMILES: OC1=CC(Br)=C(/C=N/N2C(SC)=NN=C2C3=CC=CC=C3)C=C1OC
Biological Activity: (E/Z)-GO289 is a potent and selective casein kinase 2 (CK2) inhibitor (IC50=7 nM). (E/Z)-GO289 strongly lengthens circadian period. (E/Z)-GO289 exhibits cell type–dependent inhibition of cancer cell growth that correlated with cellular clock function[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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(E/Z)-GO289 | 98.98% | (E/Z)-GO289 is a potent and selective casein kinase 2 (CK2) inhibitor (IC50=7 nM). (E/Z)-GO289 strongly lengthens circadian period. (E/Z)-GO289 exhibits cell type–dependent inhibition of cancer cell growth that correlated with cellular clock function. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.50
HY-121085CID-663143 -
Similarity Score 0.50
HY-149668α-Glucosidase-IN-41 -
Similarity Score 0.50
HY-128005ML085 -
Similarity Score 0.49
HY-155973Urease-IN-8 -
Similarity Score 0.48
HY-146987FWM-3 -
Similarity Score 0.48
HY-155970Urease-IN-7 -
Similarity Score 0.47
HY-139731Transketolase-IN-1 -
Similarity Score 0.47
HY-146198COX-2-IN-19 -
Similarity Score 0.47
HY-103050ML-030 -
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